OX1 Receptors
The OX1 receptors, also known as hypocretin receptor 1, are located primarily in the ventromedial hypothalamus, locus coeruleus, median raphe, hippocampus and taenia tecta where they are thought to regulate sleep-wakefulness and energy homeostasis, particularly food intake.
OX1 Receptor Agonists |
|
|---|---|
| Cat. No. | 产品名称/活性 |
| 5115 | OXA (17-33) |
| Potent and selective peptide OX1 agonist | |
OX1 Receptor Antagonists |
|
| Cat. No. | 产品名称/活性 |
| 4983 | ACT 335827 |
| Potent and selective OX1 antagonist | |
| 1960 | SB 334867 |
| Selective non-peptide OX1 antagonist | |
| 1963 | SB 408124 |
| Selective non-peptide OX1 antagonist | |
| 4673 | SB 674042 |
| Potent and selective non-peptide OX1 antagonist | |
The OX1 receptors, also known as hypocretin receptor 1, are located primarily in the ventromedial hypothalamus, locus coeruleus, median raphe, hippocampus and taenia tecta where they are thought to regulate sleep-wakefulness and energy homeostasis. The OX1 receptor displays higher affinity for Orexin A over Orexin B. The human OX1 receptor gene has been localized to chromosome 1 (1p33).
External sources of pharmacological information for OX1 Receptors :
Literature for OX1 Receptors
Tocris offers the following scientific literature for OX1 Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Our Peptides Involved in Appetite Modulation review gives an overview of the peptides implicated in appetite regulation and energy homeostasis.
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