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2,3-DCPE hydrochloride

Cat. No. 2137 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2137 has been discontinued.

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说明： Selectively induces cancer cell apoptosis
化学名： 2-[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol hydrochloride
纯度： ≥99% (HPLC)
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生物活性 技术数据 说明书 参考文献

生物活性 for 2,3-DCPE hydrochloride

2,3-DCPE hydrochloride is a selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.

技术数据 for 2,3-DCPE hydrochloride

分子量 300.61
公式 C11H15Cl2NO2.HCl
储存 Desiccate at -20°C
纯度 ≥99% (HPLC)
CAS Number 1009555-55-8
PubChem ID 52913859
InChI Key GFCJFYSIPRIHKT-UHFFFAOYSA-N
Smiles Cl.OCCNCCCOC1=C(Cl)C(Cl)=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

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产品说明书 for 2,3-DCPE hydrochloride

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Programmed Cell Death Poster

Programmed Cell Death Poster

There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

Pathways for 2,3-DCPE hydrochloride

Apoptosis Signaling Pathway

Apoptosis Signaling Pathway

Apoptosis is a physiological process for cell death that is critical during aging and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.