5-Ethynyluridine

Cat. No. 7206 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Uridine analog, used for labeling RNA synthesis

化学名： 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione

纯度： ≥98% (HPLC)

文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for 5-Ethynyluridine

5-Ethynyluridine is a cell-permeable uridine analog. 5-Ethynyluridine can be used in vitro and in vivo to label newly synthesized RNA. 5-Ethynyluridine can be used to study changes in transcription.

技术数据 for 5-Ethynyluridine

分子量	268.23
公式	C₁₁H₁₂N₂O₆
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	69075-42-9
PubChem ID	14885960
InChI Key	QCWBIPKYTBFWHH-FDDDBJFASA-N
Smiles	OC[C@H]1O[C@@H](N2C=C(C(NC2=O)=O)C#C)[C@@H]([C@@H]1O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 5-Ethynyluridine

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	13.41	50
	DMSO	26.82	100

制备储备液 for 5-Ethynyluridine

以下数据基于产品分子量 268.23。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.73 mL	18.64 mL	37.28 mL
5 mM	0.75 mL	3.73 mL	7.46 mL
10 mM	0.37 mL	1.86 mL	3.73 mL
50 mM	0.07 mL	0.37 mL	0.75 mL

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产品说明书 for 5-Ethynyluridine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for 5-Ethynyluridine

参考文献是支持产品生物活性的出版物。

Nainar et al (2020) An optimized chemical-genetic method for cell-specific metabolic labeling of RNA. Nat.Methods 17 311 PMID: 32015544

Van't Sant et al (2021) In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. Acta Neuropathol.Commun. 9 94 PMID: 34020718

If you know of a relevant reference for 5-Ethynyluridine, please let us know.

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关键词: 5-Ethynyluridine, 5-Ethynyluridine supplier, 5ethynyluridine, uracil, uridine, transcription, RNA, proliferation, 5EUd, analogs, analogues, DNA,, and, Protein, Synthesis, Biochemicals, Molecular, Biology, 7206, Tocris Bioscience

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