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Submit Review5-InoAz is a metabolic probe for labeling the mycobacterium cell envelope. Specifically designed as an inositol analog to incorportate into cell envelope glycolipids (phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM) and lipoarabinomannan (LAM)). In combination with bioorthogonal chemistry, it provides a valuable tool for investigating PIM, LM, and LAM biosynthesis, transport, and dynamics in diverse mycobacterial organisms.
分子量 | 205.17 |
公式 | C6H11N3O5 |
储存 | Store at -20°C |
纯度 | ≥90% (HPLC) |
CAS Number | 1218932-97-8 |
PubChem ID | 102168607 |
InChI Key | KTRSBMDLCXWFCL-ZYNIPDFASA-N |
Smiles | O[C@@H]([C@@H]([C@@H]([C@@H]([C@H]1O)O)O)O)[C@H]1N=[N+]=[N-] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 20.52 | 100 | |
DMSO | 20.52 | 100 |
以下数据基于产品分子量 205.17。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 4.87 mL | 24.37 mL | 48.74 mL |
5 mM | 0.97 mL | 4.87 mL | 9.75 mL |
10 mM | 0.49 mL | 2.44 mL | 4.87 mL |
50 mM | 0.1 mL | 0.49 mL | 0.97 mL |
参考文献是支持产品生物活性的出版物。
Hodges et al (2023) Azido inositol probes enable metabolic labeling of inositol-containing glycans and reveal an inositol importer in mycobacteria. ACS Chem.Biol. 18 595 PMID: 36856664
If you know of a relevant reference for 5-InoAz, please let us know.
关键词: 5-InoAz, 5-InoAz supplier, metabolic, probe, analogue, labeling, bacteria, labels, labelling, imaging, mycobacteria, glycolipid, PIM, LM, LAM, bioorthogonal, chemistry, inositol, phosphatidylinositol, mannoside, anchored, lipomannan, lipoarabinomannan, Glycobiology, Probes, Fluorescent, for, Imaging, Bacteria, 7973, Tocris Bioscience
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