主页 / Product Type / Optopharmacology / Photoactivatable Cross-linking Probes / AbK

AbK

Cat. No. 5113 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Photo-crosslinking probe; unnatural amino acid
化学名： N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for AbK

AbK is an unnatural amino acid. Acts as a UV light-activated (369 nm) photocrosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUA pairs.

技术数据 for AbK

分子量 272.3
公式 C11H20N4O4.CF3CO2H
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1253643-88-7
PubChem ID 66825403
InChI Key LUCMNTLJAFTFDU-QMMMGPOBSA-N
Smiles N[C@H](C(O)=O)CCCCNC(OCCC1(C)N=N1)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for AbK

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 2.72 10 温和加热
1eq. HCl 27.23 100

制备储备液 for AbK

以下数据基于产品分子量 272.3。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.67 mL 18.36 mL 36.72 mL
5 mM 0.73 mL 3.67 mL 7.34 mL
10 mM 0.37 mL 1.84 mL 3.67 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

Molarity Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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参考文献 for AbK

参考文献是支持产品生物活性的出版物。

Ai et al (2011) Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem 12 1854 PMID: 21678540

Chatterjee et al (2013) Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc.Natl.Acad.Sci.U.S.A. 110 11803 PMID: 23818609

Lowder et al (2011) Visualizing protein partnerships in living cells and organisms. Curr.Opin.Cell Biol. 15 781 PMID: 22104179

Kleiner et al (2018) A chemical proteomics approach to reveal direct protein-protein interactions in living cells. Cell Chem.Biol. 25 110 PMID: 29104064

If you know of a relevant reference for AbK, please let us know.

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关键词: AbK, AbK supplier, photo-crosslinking, amino, acids, UV, light, tRNA, synthetase, pairs, reagents, photocrosslinking, unnatural, acid, UAA, Biochemicals, and, Molecular, Biology, Unnatural, Amino, Acids, Photoactivatable, cross-linking, probes, 5113, Tocris Bioscience

1 篇 AbK 的引用文献

引用文献是使用了 Tocris 产品的出版物。 AbK 的部分引用包括：

Syed et al (2019) Expanding the Zebrafish Genetic Code through Site-Specific Introduction of Azido-lysine, Bicyclononyne-lysine, and Diazirine-lysine. Int J Mol Sci 20 PMID: 31130675

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