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Ac4GalN6yne

Cat. No. 7932 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Alkyne containing monosaccharide building block; used in BOCTAG
化学名： 2-Deoxy-2-[(1-oxo-5-hexyn-1-yl)amino]-D-galactopyranose-1,3,4,6-tetraacetate
纯度： ≥95% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Ac4GalN6yne

Ac4GalN6yne is a cell-permeable alkyne-containing monosaccharide building block. It can be used in Bio-Orthogonal Cell-specific Tagging of Glycoproteins (BOCTAG) technique. In this strategy, cells carrying an artificial biosynthetic pathway (B. longum NahK and mut-AGX1) can generate alkyne-tagged UDP-GalN6yne, that are then used by glycosyltransferases to chemically tag the glycoproteome. Ac4GalN6yne can be used for bioorthogonal labelling in vitro and mouse models.

技术数据 for Ac4GalN6yne

分子量 441.43
公式 C20H27NO10
储存 Store at -20°C
纯度 ≥95% (HPLC)
InChI Key RWQXKPQZNDMFQH-FIBJEGPVSA-N
Smiles O=C(N[C@@H]1[C@H]([C@H]([C@H](OC1OC(C)=O)COC(C)=O)OC(C)=O)OC(C)=O)CCCC#C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Ac4GalN6yne

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 8.83 20 温和加热

制备储备液 for Ac4GalN6yne

以下数据基于产品分子量 441.43。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.2 mM 11.33 mL 56.63 mL 113.27 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
2 mM 1.13 mL 5.66 mL 11.33 mL
10 mM 0.23 mL 1.13 mL 2.27 mL

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参考文献 for Ac4GalN6yne

参考文献是支持产品生物活性的出版物。

Cioce et al (2022) Cell-specific bioorthogonal tagging of glycoproteins. Nat.Commun. 13 6237 PMID: 36284108

If you know of a relevant reference for Ac4GalN6yne, please let us know.

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关键词: Ac4GalN6yne, Ac4GalN6yne supplier, cell-permeable, building, block, glycoproteins, glycolipids, probes, probe, post-translational, modifications, glycobiology, monosaccharide, BOCTAG, alkyne, tagged, UDP-GalN6yne, bioorthogonal, , in, vivo, Glycobiology, Probes, Biochemicals, and, Molecular, Biology, Post-translational, Modifications, 7932, Tocris Bioscience

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