主页 / 药理学 / Enzymes / Proteases / Other Proteases / Other Protease Inhibitors / AEBSF

AEBSF

Cat. No. 5175 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Broad spectrum, irreversible inhibitor of serine proteases
化学名： 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for AEBSF

AEBSF is a broad spectrum, irreversible inhibitor of serine proteases. Also inhibits NADPH oxidase activation in vitro. Attenuates airway inflammation in a mouse model of airway allergy.

化合物库 for AEBSF

AEBSF is also offered as part of the Tocriscreen Antiviral Library. 了解 Tocris 化合物库的更多信息。

技术数据 for AEBSF

分子量 239.69
公式 C8H10FNO2S.HCl
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 30827-99-7
PubChem ID 186136
InChI Key WRDABNWSWOHGMS-UHFFFAOYSA-N
Smiles NCCC1=CC=C(S(=O)(F)=O)C=C1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for AEBSF

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 23.97 100
DMSO 23.97 100

制备储备液 for AEBSF

以下数据基于产品分子量 239.69。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.17 mL 20.86 mL 41.72 mL
5 mM 0.83 mL 4.17 mL 8.34 mL
10 mM 0.42 mL 2.09 mL 4.17 mL
50 mM 0.08 mL 0.42 mL 0.83 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

产品说明书 for AEBSF

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for AEBSF

参考文献是支持产品生物活性的出版物。

Diatchuk et al (1997) Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. J.Biol.Chem. 272 13292 PMID: 9148950

Saw et al (2012) Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease. PLoS ONE 7 e41107 PMID: 22829914

If you know of a relevant reference for AEBSF, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Other Protease Inhibitors

关键词: AEBSF, AEBSF supplier, broad, spectrum, irreversible, serine, proteases, inhibitors, inhibits, trypsin, chymotrypsin, plasmin, thrombin, kallikreins, Other, Proteases, 5175, Tocris Bioscience

1 篇 AEBSF 的引用文献

引用文献是使用了 Tocris 产品的出版物。 AEBSF 的部分引用包括：

Xianglan et al (2019) Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects. J Allergy Clin Immunol 144 426-441.e3 PMID: 30872118

您是否知道使用了 Tocris AEBSF 的优秀论文？ 请告知我们.

AEBSF 的评论

目前没有该产品的评论。 Be the first to review AEBSF and earn rewards!

Have you used AEBSF?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review