主页 / 药理学 / Enzymes / Kinases / PI 3-kinase / PI 3-kinase Inhibitors / AS 252424

AS 252424

Cat. No. 3671 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3671 has been discontinued.

View all PI 3-kinase products.
说明： Selective inhibitor of PI 3-kinase γ
化学名： 5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for AS 252424

AS 252424 is a potent and selective inhibitor of PI 3-kinase γ (IC50 values are 33 and 935 nM for PI 3-Kγ and PI 3-Kα respectively).

技术数据 for AS 252424

分子量 305.28
公式 C14H8FNO4S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 900515-16-4
PubChem ID 11630874
InChI Key OYYVWNDMOQPMGE-SDQBBNPISA-N
Smiles OC1=CC(F)=CC=C1C2=CC=C(\C=C3/SC(NC3=O)=O)O2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for AS 252424

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for AS 252424

参考文献是支持产品生物活性的出版物。

Condliffe et al (2005) Sequential activation of class IB and IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood 106 1432 PMID: 15878979

Pomel et al (2006) Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ. J.Med.Chem. 49 3857 PMID: 16789742

按标靶查看相关产品

按产品操作查看相关产品

查看全部 PI 3-kinase Inhibitors

关键词: AS 252424, AS 252424 supplier, PI3Kgamma, PI3Kγ, PI, 3-kinasegamma, 3-kinaseg, 3-kinaseγ, phosphoinositide, 3, kinases, gamma, γ, signalling, signaling, inositol, lipids, selective, inhibitors, inhibits, AS252424, pi3k, 3-Kinase, 3671, Tocris Bioscience

1 篇 AS 252424 的引用文献

引用文献是使用了 Tocris 产品的出版物。 AS 252424 的部分引用包括：

Schepetkin et al (2012) Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors. Mol Pharmacol 81 832 PMID: 22434859

AS 252424 的评论

目前没有该产品的评论。 Be the first to review AS 252424 and earn rewards!

Have you used AS 252424?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review