Autocamtide-2-related inhibitory peptide, myristoylated

Cat. No. 5959 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide

别名： Myr-AIP,AIP Myristoylated

纯度： ≥95% (HPLC)

生物活性技术数据溶解性计算器说明书参考文献

生物活性

Autocamtide-2-related inhibitory peptide, myristoylated is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide (Cat No. 1688). Pretreatment blocks reinstatement of morphine-seeking behavior in vivo.

技术数据

分子量	1708.12
公式	C₇₈H₁₄₂N₂₂O₂₀
序列	KKALRRQEAVDAL (Modifications: Lys-1 = Myr-Lys)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	201422-04-0
PubChem ID	121513908
InChI Key	QKOOKZWMKXOQRL-YJDHHEDVSA-N
Smiles	[H]N[C@@H](CCCCNC(=O)CCCCCCCCCCCCC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

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溶解性数据

溶解性	Soluble to 1 mg/ml in water

产品说明书

分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Laabich et al (2000) Neuroprotective effect of AIP on N-methyl-D-aspartate-induced cell death in retinal neurons. Brain Res.Mol.Brain Res. 85 32 PMID: 11146104

Liu et al (2012) Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Neurosci.Lett. 518 167 PMID: 22579819

Ishida et al (1995) A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem.Biophys.Res.Commun. 212 806 PMID: 7626114

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