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Azathioprine

Cat. No. 4099 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4099 has been discontinued.

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说明： Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103)
化学名： 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
纯度： ≥99% (HPLC)
说明书
引用文献
评论 (1)
文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for Azathioprine

Azathioprine is a purine analog. Blocks DNA replication and the de novo pathway of purine synthesis. Immunosuppressive and anti-inflammatory drug; induces apoptosis in human T-lymphocytes. Prodrug of 6-mercaptopurine (Cat. No. 4103).

化合物库 for Azathioprine

Azathioprine is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Azathioprine

分子量 277.26
公式 C9H7N7O2S
储存 Store at -20°C
纯度 ≥99% (HPLC)
CAS Number 446-86-6
PubChem ID 2265
InChI Key LMEKQMALGUDUQG-UHFFFAOYSA-N
Smiles CN1C=NC([N+]([O-])=O)=C1SC2=C3C(N=CN3)=NC=N2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Azathioprine

参考文献是支持产品生物活性的出版物。

Maltzman and Koretzky (2003) Azathioprine: old drug, new actions. J.Clin.Invest. 111 1122 PMID: 12697731

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关键词: Azathioprine, Azathioprine supplier, Azathioprine, immunosuppressant, inhibits, DNA, synthesis, inhibitors, lymphocyte, purine, analog, DNA,, RNA, and, Protein, Synthesis, Immunosuppressants, 4099, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Azathioprine, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

篇 Azathioprine 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Azathioprine 的引用文献。

Azathioprine 的评论

平均评分: 5 (Based on 1 Review.)

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Medium concentration of azathioprine slows growth but does not kill melanoma cells in vitro.
By Anonymous on 02/14/2019
分析类型： In Vitro
种属： Human

Azathioprine was used at a 20 uM concentration for in vitro culture with SK-MEL-28 and cell viability was monitored over time with live imaging. Arrow indicates when compound was added to media.

review image

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

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