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BAM 7

Cat. No. 4810 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4810 has been discontinued.

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说明： Selective Bax activator; induces Bax-mediated apoptosis
化学名： 3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]
纯度： ≥99% (HPLC)
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引用文献
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文献 (2)
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生物活性 技术数据 说明书 参考文献

生物活性 for BAM 7

BAM 7 is a Bax activator (EC50 = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic proteins. Triggers Bax oligomerization in vitro; induces Bax-mediated apoptosis in mouse embryonic fibroblasts.

技术数据 for BAM 7

分子量 405.47
公式 C21H19N5O2S
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 331244-89-4
PubChem ID 5754137
InChI Key KOCVKGYKBLJEPK-LYBHJNIJSA-N
Smiles CC(/C1=N\NC2=C(OCC)C=CC=C2)=NN(C3=NC(C4=CC=CC=C4)=CS3)C1=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BAM 7

参考文献是支持产品生物活性的出版物。

Gavathiotis et al (2012) Direct and selective small-molecule activation of proapoptotic BAX. Nat.Chem.Biol. 8 639 PMID: 22634637

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关键词: BAM 7, BAM 7 supplier, BAM7, bax, proapoptotic, apoptosis, activators, BH3, binding, site, inducers, oligomerization, selective, Bcl-2, Family, Apoptosis, Inducers, 4810, Tocris Bioscience

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