Bryostatin 3

Discontinued Product

5238 has been discontinued.

View all Protein Kinase C products.
说明: Potent protein kinase C activator
化学名: (4S,5S,7E,9R,11Z,13S,15S,17S,19R,21R,25R,27R,27aS)-17-(Acetyloxy)-4,5,6,9,10,11,12,13,14,15,16,17,18,19, 20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-[(1R)-1-hydroxyethyl]-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl-(2E,4E)-2,4-octadienoic acid ester
纯度: ≥95% (HPLC)
说明书
引用文献
评论

生物活性 for Bryostatin 3

Bryostatin 3 is a potent protein kinase C activator (KI = 2.75 nM). Attenuates phorbol 12-myristate 13-acetate (Cat. No. 1201) inhibition of GH4C1 pituitary cell proliferation in vitro.

技术数据 for Bryostatin 3

分子量 888.99
公式 C46H64O17
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 143370-84-7
PubChem ID 10395929
InChI Key BSNHYLUEHJOXFN-HBUIWOJHSA-N
Smiles O=C(O[C@@H]([C@@H](C)O)C[C@@H](O5)[C@H]3O4)C[C@H](O)C[C@H](C[C@H](OC(C)=O)C(C)2C)O[C@@]2(O)C[C@H](C1)O[C@@H](/C=C/C(C)(C)[C@@]5(O)[C@@H](OC(/C=C/C=C/CCC)=O)C3=CC4=O)C/C1=C\C(OC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Bryostatin 3

参考文献是支持产品生物活性的出版物。

Mackanos et al (1991) BryoSTAT selectively regulate protein kinase C-mediated effects on GH4 cell proliferation. J.Biol.Chem. 266 1120 PMID: 1904062

Wender et al (1988) Modeling of the bryoSTAT to the phorbol ester pharmacophore on protein kinase C. Proc.Natl.Acad.Sci.U.S.A. 85 7197 PMID: 3174627

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关键词: Bryostatin 3, Bryostatin 3 supplier, potent, protein, kinases, c, activator, Bryostatin, 3, natural, Protein, Kinase, C, 5238, Tocris Bioscience

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