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Submit ReviewBryostatin 3 is a potent protein kinase C activator (KI = 2.75 nM). Attenuates phorbol 12-myristate 13-acetate (Cat. No. 1201) inhibition of GH4C1 pituitary cell proliferation in vitro.
分子量 | 888.99 |
公式 | C46H64O17 |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 143370-84-7 |
PubChem ID | 10395929 |
InChI Key | BSNHYLUEHJOXFN-HBUIWOJHSA-N |
Smiles | O=C(O[C@@H]([C@@H](C)O)C[C@@H](O5)[C@H]3O4)C[C@H](O)C[C@H](C[C@H](OC(C)=O)C(C)2C)O[C@@]2(O)C[C@H](C1)O[C@@H](/C=C/C(C)(C)[C@@]5(O)[C@@H](OC(/C=C/C=C/CCC)=O)C3=CC4=O)C/C1=C\C(OC)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Mackanos et al (1991) BryoSTAT selectively regulate protein kinase C-mediated effects on GH4 cell proliferation. J.Biol.Chem. 266 1120 PMID: 1904062
Wender et al (1988) Modeling of the bryoSTAT to the phorbol ester pharmacophore on protein kinase C. Proc.Natl.Acad.Sci.U.S.A. 85 7197 PMID: 3174627
关键词: Bryostatin 3, Bryostatin 3 supplier, potent, protein, kinases, c, activator, Bryostatin, 3, natural, Protein, Kinase, C, 5238, Tocris Bioscience
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