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BzF

Cat. No. 6786 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6786 has been discontinued.

View all Photoactivatable Cross-linking Probes products.
说明： Photoreactive unnatural amino acid; photo-crosslinker
化学名： 4-Benzoyl-L-phenylalanine
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for BzF

BzF is a photoreactive unnatural amino acid. Acts as photo cross-linking probe when incorporated into proteins, including ion channels, transporters and GPCRs. When exposed to UV light it forms a covalent cross-link with a C-H bond-containing group, enabling selective and potent UV-driven photoinactivation of protein function. Has been used to study protein-protein and protein-ligand interactions.

技术数据 for BzF

分子量 269.3
公式 C16H15NO3
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 104504-45-2
PubChem ID 7020128
InChI Key TVIDEEHSOPHZBR-AWEZNQCLSA-N
Smiles N[C@H](C(O)=O)CC1=CC=C(C(C2=CC=CC=C2)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BzF

参考文献是支持产品生物活性的出版物。

Ye et al (2008) Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J.Biol.Chem. 283 1525 PMID: 17993461

Klippenstein et al (2018) Probing ion channel structure and function using light-sensitive amino acids. Trends Biochem.Sci. 43 436 PMID: 29650383

Klippenstein et al (2014) Photoinactivation of glutamate receptors by genetically encoded unnatural amino acids. J.Neurosci. 34 980 PMID: 24431456

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