主页 / 细胞生物学 / Cell Metabolism / DNA, RNA and Protein Synthesis / CEP

CEP

Cat. No. 8108 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells
化学名： 2,6-Dichloro-7-(2-propyn-1-yl)-7H-purine
纯度： ≥98% (HPLC)
说明书
引用文献
评论
文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for CEP

CEP is a chemoproteomic reagent. It is a clickable electrophilic purine used to directly quantify protein-RNA interactions on proteins through photoaffinity competition with 4-thiouridine (4SU)-labeled RNA in cells. It is a cysteine reactive probe used in photo-activatable-competition and chemoproteomic enrichment (PACCE) method for global quantification of protein-RNA interactions in living cells.

技术数据 for CEP

分子量 227.05
公式 C8H4Cl2N4
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1838570-66-3
PubChem ID 155590179
InChI Key DQZMJDUCMIRFBJ-UHFFFAOYSA-N
Smiles ClC1=NC(N=CN2CC#C)=C2C(Cl)=N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for CEP

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 22.7 100
ethanol 2.27 10 温和加热

制备储备液 for CEP

以下数据基于产品分子量 227.05。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.4 mL 22.02 mL 44.04 mL
5 mM 0.88 mL 4.4 mL 8.81 mL
10 mM 0.44 mL 2.2 mL 4.4 mL
50 mM 0.09 mL 0.44 mL 0.88 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for CEP

参考文献是支持产品生物活性的出版物。

Heindel et al (2023) Chemoproteomic capture of RNA binding activity in living cells. Nat.Commun. 14 6282 PMID: 37805600

If you know of a relevant reference for CEP, please let us know.

按标靶查看相关产品

关键词: CEP, CEP supplier, Chemoproteomic, reagent, clickable, electrophilic, purine, RNA, protein, binding, profiling, PACCE, photoactivatable, competition, and, chemoproteomic, enrichment, DNA,, Protein, Synthesis, Biochemicals, Molecular, Biology, 8108, Tocris Bioscience

篇 CEP 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 CEP 的引用文献。 您是否知道使用了 Tocris CEP 的优秀论文？ 请告知我们.

CEP 的评论

目前没有该产品的评论。 Be the first to review CEP and earn rewards!

Have you used CEP?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Cell Cycle and DNA Damage Research Product Guide

Cell Cycle and DNA Damage Research Product Guide

This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:

  • Cell Cycle and Mitosis
  • DNA Damage Repair
  • Targeted Protein Degradation
  • Ubiquitin Proteasome Pathway
  • Chemotherapy Targets
Huntington's Disease Research Product Guide

Huntington's Disease Research Product Guide

This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:

  • Somatic Instability
  • Proteolysis and Inclusion Bodies
  • Transcriptional Dysregulation
  • Mitochondrial Dysfunction
  • Nuclear-Cytoplasmic Transport Interference
  • Excitotoxicity
  • Stem Cells