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CID 2011756

Cat. No. 4644 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4644 has been discontinued.

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说明： Pan protein kinase D (PKD) inhibitor; cell permeable
化学名： 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
纯度： ≥99% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for CID 2011756

CID 2011756 is a protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50 = 10 μM for PKD1 inhibition). ATP-competitive.

技术数据 for CID 2011756

分子量 396.87
公式 C22H21ClN2O3
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 638156-11-3
PubChem ID 2011756
InChI Key XQJWTJLJEYIUDZ-UHFFFAOYSA-N
Smiles O=C(NC3=CC=C(CN4CCOCC4)C=C3)C1=CC=C(C2=CC=CC(Cl)=C2)O1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for CID 2011756

参考文献是支持产品生物活性的出版物。

Sharlow et al (2011) Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One 6 e25134 PMID: 21998636

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关键词: CID 2011756, CID 2011756 supplier, CID2011756, pan, protein, kinase, D, PKD, inhibits, inhibitors, cell, permeable, ATP, competitive, Protein, Kinase, 4644, Tocris Bioscience

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