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Discontinued Product
6117 has been discontinued.
说明： Carbon monoxide-releasing molecule
化学名： Tricarbonyldichlororuthenium(II) dimer
生物活性 for CORM 2
CORM 2 is a carbon monoxide-releasing molecule. Causes vasodilatation in isolated aortic rings in vitro. Cytotoxic to smooth muscle cells in vitro after prolonged (24h) exposure. Exhibits antihypertensive effects in vivo. Reduces tight-junction disruption in intestinal mucosa in a rat sepsis model.
技术数据 for CORM 2
| 分子量 | 512.01 |
| 公式 | C6Cl4O6Ru2 |
| 储存 | Store at RT |
| CAS Number | 22594-69-0 |
| PubChem ID | 10951331 |
| InChI Key | JYHHJVKGDCZCCL-UHFFFAOYSA-J |
| Smiles | [Cl-][Ru++]1([Cl-][Ru++]([Cl-])([Cl-]1)(C#[O])(C#[O])C#[O])(C#[O])(C#[O])C#[O] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for CORM 2
参考文献 for CORM 2
参考文献是支持产品生物活性的出版物。
Zhang et al (2015) Carbon monoxide-releasing molecule-2 reduces intestinal epithelial tight-junction damage and mortality in septic rats. PLoS One 10 e0145988 PMID: 26720630
Motterlini et al (2002) Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ.Res. 90 E17 PMID: 11834719
关键词: CORM 2, CORM 2 supplier, CORM2, CO, carbon, monoxide, releasing, moleculea, antihypertensives, vasorelaxant, ROS, Donors, Miscellaneous, Compounds, 6117, Tocris Bioscience
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