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Submit Review(D)-(+)-Neopterin is a precursor of biopterin synthesis. Synthesized in response to interferon-γ stimulation; used as a marker of T helper cell-induced immune activation. Also an indicator of oxidative stress; modulates the effects of reactive oxygen species (ROS).
(D)-(+)-Neopterin is also offered as part of the Tocriscreen Antiviral Library. 了解 Tocris 化合物库的更多信息。
分子量 | 253.21 |
公式 | C9H11N5O4 |
储存 | Store at -20°C |
纯度 | ≥98% (HPLC) |
CAS Number | 2009-64-5 |
PubChem ID | 448839 |
InChI Key | BMQYVXCPAOLZOK-XINAWCOVSA-N |
Smiles | OC[C@@H](O)[C@@H](O)C2=NC1=C(N=C2)N=C(N)NC1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Murr et al (2002) Neopterin as a marker for immune system activation. Curr.Drug Metab. 3 175 PMID: 12003349
Huber et al (1984) Immune response-associated production of neopterin. J.Exp.Med. 160 310 PMID: 6429267
关键词: (D)-(+)-Neopterin, (D)-(+)-Neopterin supplier, cytokines, IFN-gamma, IFN-g, IFN-γ, immune, markers, oxidative, stress, indicators, Cytokines, 4656, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 (D)-(+)-Neopterin 的部分引用包括:
Kaminska et al (2016) Highly efficient SERS-based detection of cerebrospinal fluid neopterin as a diagnostic marker of bacterial infection. J Neurochem 408 4319 PMID: 27086021
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.