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Submit Review(±)-CPSI 1306 is reported to be a macrophage inhibitory factor (MIF) inhibitor.
This product is racemic.
(±)-CPSI 1306 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Antiviral Library. 了解 Tocris 化合物库的更多信息。
分子量 | 310.3 |
公式 | C15H16F2N2O3 |
储存 | Store at -20°C |
纯度 | ≥98% (HPLC) |
CAS Number | 1309793-47-2 |
PubChem ID | 59723793 |
InChI Key | GUWOSEVHCSNYFK-UHFFFAOYSA-N |
Smiles | FC(C=C2F)=CC=C2C1=NOC(CC(N3CCOCC3)=O)C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Kithcart et al (2010) A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease. FASEB J. 24 4459 PMID: 20624927
Sanchez-Zamora et al (2010) Macrophage migration inhibitory factor is a therapeutic target in treatment of non-Ins-dependent diabetes mellitus. FASEB J. 24 2583 PMID: 20203087
关键词: (±)-CPSI 1306, (±)-CPSI 1306 supplier, macrophage, migration, inhibitory, factor, MIF, inhibits, inhibitors, dopachrome, tautomerase, multiple, sclerosis, inflammatory, cytokines, CPSI1306, Cytokines, 4400, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.