H-9 dihydrochloride

Name: H-9 dihydrochloride
Brand: Tocris Bioscience
SKU: 0396

Cat. No. 0396 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0396 has been discontinued.

View all Broad Spectrum Protein Kinase Inhibitors products.

说明： Protein kinase inhibitor

化学名： N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for H-9 dihydrochloride

Protein kinase inhibitor. Inhibits PKA (K_i = 1.9 μM), PKG (K_i = 0.9 μM), CaMK II (K_i = 60 μM), PKC (K_i = 18 μM), casein kinase I (K_i = 110 μ M) and casein kinase II (K_i > 300 μM).

技术数据 for H-9 dihydrochloride

分子量	324.22
公式	C₁₁H₁₃N₃O₂S.2HCl
储存	Desiccate at RT
纯度	≥99% (HPLC)
CAS Number	116700-36-8
PubChem ID	2735333
InChI Key	HBLCYSFLYMHCBM-UHFFFAOYSA-N
Smiles	Cl.Cl.NCCNS(=O)(=O)C1=CC=CC2=CN=CC=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for H-9 dihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for H-9 dihydrochloride

参考文献是支持产品生物活性的出版物。

Hidaka et al (1984) Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23 5036 PMID: 6238627

Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Annu.Rev.Pharmacol.Toxicol. 32 377 PMID: 1605572

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