主页 / 药理学 / Enzymes / Kinases / Haspin / Haspin Inhibitors / LDN 209929 dihydrochloride

LDN 209929 dihydrochloride

Cat. No. 4828 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4828 has been discontinued.

View all Haspin products.
说明： Potent and selective haspin inhibitor
化学名： 3-[(2-Chloro-7-methoxy-9-acridinyl)thio]-1-propanamine dihydrochloride
纯度： ≥98% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for LDN 209929 dihydrochloride

LDN 209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50 = 55 nM). Displays 180-fold selectivity over DYRK2.

技术数据 for LDN 209929 dihydrochloride

分子量 405.77
公式 C17H17ClN2OS.2HCl
储存 Desiccate at RT
纯度 ≥98% (HPLC)
CAS Number 1784281-97-5
PubChem ID 90488975
InChI Key WOCCOXNODBCCGK-UHFFFAOYSA-N
Smiles ClC1=CC=C(N=C(C=CC(OC)=C3)C3=C2SCCCN)C2=C1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for LDN 209929 dihydrochloride

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for LDN 209929 dihydrochloride

参考文献是支持产品生物活性的出版物。

Cuny et al (2010) Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg.Med.Chem.Lett. 20 3491 PMID: 20836251

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Haspin Inhibitors

关键词: LDN 209929 dihydrochloride, LDN 209929 dihydrochloride supplier, LDN209929, dihydrochloride, haploid, germ, cells, specific, nuclear, protein, haspin, kinases, gsg2, mitosis, potent, selective, Haspin, 4828, Tocris Bioscience

篇 LDN 209929 dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 LDN 209929 dihydrochloride 的引用文献。

LDN 209929 dihydrochloride 的评论

目前没有该产品的评论。 Be the first to review LDN 209929 dihydrochloride and earn rewards!

Have you used LDN 209929 dihydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Cell Cycle & DNA Damage Repair Poster

Cell Cycle & DNA Damage Repair Poster

In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. This poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.