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Submit ReviewProtein kinase C activator. Exhibits tumor promoting activity. Directs differentiation of human embryonic stem cells (ESCs) into pancreatic progenitors.
分子量 | 301.38 |
公式 | C17H23N3O2 |
储存 | Desiccate at -20°C |
纯度 | ≥99% (HPLC) |
CAS Number | 90365-57-4 |
Smiles | O=C(N[C@@H](C3)CO)[C@H]([C@H](C)C)N(C)C1=CC=CC2=C1C3=CN2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Geiges et al (1997) Activation of protein kinase C subtypes α, γ, δ, ε, ζ and η by tumor-promoting and nontumor-promoting agents. Biochem.Pharmacol. 53 865 PMID: 9113106
Masuda et al (2002) Binding selectivity of conformationally restricted analogues of (-)-indolactam-V to the C1 domains of protein kinase C isozymes. Biosci.Biotechnol.Biochem. 66 1615 PMID: 12224655
Chen et al (2009) A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat.Chem.Biol. 5 258 PMID: 19287398
关键词: (-)-Indolactam V, (-)-Indolactam V supplier, Protein, kinases, C, activators, PKC, (-)-IndolactamV, Kinase, Enzyme, Substrates, /, Activators, 3651, Tocris Bioscience
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