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Muristerone A

Cat. No. 3816 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3816 has been discontinued.

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说明： Stimulates Bcl-XL mRNA transcription; antiapoptotic
化学名： (2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one
纯度： ≥97% (HPLC)
说明书
引用文献
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文献 (2)
通路 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for Muristerone A

Muristerone A is an ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

技术数据 for Muristerone A

分子量 496.63
公式 C27H44O8
储存 Store at -20°C
纯度 ≥97% (HPLC)
CAS Number 38778-30-2
PubChem ID 122217
InChI Key LRJUYAVTHIEHAI-LHBNDURVSA-N
Smiles O[C@@H]1[C@H](O)C[C@](C(C=C3[C@@]([H])2[C@H](O)C[C@@]4(C)[C@](O)3CC[C@@]([H])4[C@](O)(C)[C@H](O)CCC(C)C)=O)(O)[C@]2(C)C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Muristerone A

参考文献是支持产品生物活性的出版物。

Patrick et al (2001) Muristerone A-induced nerve growth factor release from genetically engineered human dermal fibroblasts for peripheral nerve tissue engineering. Tissue Eng. 7 303 PMID: 11429150

No et al (1996) Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc.Natl.Acad.Sci.USA 93 3346

Bosser and Zornig (2005) Agonists of an ecdysone-inducible mammalian expression system inhibit Fas-ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO. Cell Death Diff. 13 189

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关键词: Muristerone A, Muristerone A supplier, ecdysone, analogs, analogues, inhibits, antiapoptotic, Bcl-XL, inducing, agents, MuristeroneA, Bcl-2, Family, 3816, Tocris Bioscience

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