NVS PAK1 C

Pricing Availability   Qty
说明: Negative control of NVS PAK1 1 (Cat. No. 6132)
化学名: (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide
纯度: ≥98% (HPLC)
说明书
引用文献
评论

生物活性 for NVS PAK1 C

NVS PAK1 C is a negative control of NVS PAK1 1 (Cat. No. 6132), a potent and selective PAK1 inhibitor.

许可信息

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the NVS PAK1 1 probe summary on the SGC website.

技术数据 for NVS PAK1 C

分子量 465.91
公式 C22H23ClF3N5O
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 2250019-95-3
PubChem ID 136590564
InChI Key RVHZFZVJXGIAJF-HNNXBMFYSA-N
Smiles FC(F)CN(C(C=CC(F)=C1)=C1N=C2N[C@H]3CCN(C(N(C)C)=O)C3)C4=C2C=C(Cl)C=C4

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for NVS PAK1 C

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 46.59 100
ethanol 9.32 20

制备储备液 for NVS PAK1 C

以下数据基于产品分子量 465.91。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.15 mL 10.73 mL 21.46 mL
5 mM 0.43 mL 2.15 mL 4.29 mL
10 mM 0.21 mL 1.07 mL 2.15 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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参考文献 for NVS PAK1 C

参考文献是支持产品生物活性的出版物。

Karpov et al (2015) Optimization of a dibenzodiazepine hit to a potent and selective allosteric PAK1 inhibitor. ACS Med.Chem.Lett 6 776 PMID: 26191365


If you know of a relevant reference for NVS PAK1 C, please let us know.

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关键词: NVS PAK1 C, NVS PAK1 C supplier, NVSPAK1C, PAK, 1, inhibitors, inhibits, naeative, control, P21-activated, Kinases, 6133, Tocris Bioscience

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