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P3S

Cat. No. 7974 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments
化学名： 3-((1H-1,2,4-Triazol-1-yl)sulfonyl)pyridine
纯度： ≥95% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for P3S

P3S is a pyridine sulfonyl triazole able to modify RNA via RNA 2'-OH sulfonylation. P3S can be used for RNA SHAPE-MaP experiments in cell lines or live bacteria. It is stable in aqueous media (with half-lives of several hours) even at room temperature.

技术数据 for P3S

分子量 210.21
公式 C7H6N4O2S
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2988852-68-0
InChI Key LBQFWDRVXUJAAR-UHFFFAOYSA-N
Smiles O=S(C1=CC=CN=C1)(N2C=NC=N2)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for P3S

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 21.02 100

制备储备液 for P3S

以下数据基于产品分子量 210.21。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.76 mL 23.79 mL 47.57 mL
5 mM 0.95 mL 4.76 mL 9.51 mL
10 mM 0.48 mL 2.38 mL 4.76 mL
50 mM 0.1 mL 0.48 mL 0.95 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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参考文献 for P3S

参考文献是支持产品生物活性的出版物。

Chatterjee et al (2023) Sulfonylation of RNA 2'-OH groups. ACS Cent.Sci. 9 531 PMID: 36968531

If you know of a relevant reference for P3S, please let us know.

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关键词: P3S, P3S supplier, Reagent, RNA, sulfonylation, SHAPE, MaP, chemistry, experiments, mapping, secondary, tertiary, structures, in, vivo, DNA,, and, Protein, Synthesis, Biochemicals, Molecular, Biology, 7974, Tocris Bioscience

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