主页 / Product Type / Reagents / Labels & Stains / Pimonidazole

Pimonidazole

Cat. No. 6182 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Hypoxia detection reagent
化学名： α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
纯度： ≥98% (HPLC)
说明书
引用文献
评论 (1)
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Pimonidazole

Pimonidazole is a hypoxia detection reagent. Labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.

技术数据 for Pimonidazole

分子量 254.29
公式 C11H18N4O3
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 70132-50-2
PubChem ID 50981
InChI Key WVWOOAYQYLJEFD-UHFFFAOYSA-N
Smiles OC(CN1CCCCC1)CN2C=CN=C2[N+]([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Pimonidazole

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 25.43 100
ethanol 25.43 100

制备储备液 for Pimonidazole

以下数据基于产品分子量 254.29。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.93 mL 19.66 mL 39.33 mL
5 mM 0.79 mL 3.93 mL 7.87 mL
10 mM 0.39 mL 1.97 mL 3.93 mL
50 mM 0.08 mL 0.39 mL 0.79 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for Pimonidazole

参考文献是支持产品生物活性的出版物。

Sato et al (2016) Notch2 signaling regulates the proliferation of murine bone marrow-derived mesenchymal stem/stromal cells via c-Myc expression. PLoS One 11 e0165946 PMID: 27855169

Bennewith et al (2002) Orally administered pimonidazole to label hypoxic tumor cells. Cancer Res. 62 6827 PMID: 12460894

If you know of a relevant reference for Pimonidazole, please let us know.

按标靶查看相关产品

关键词: Pimonidazole, Pimonidazole supplier, hypoxia, detection, detects, hypoxic, in, vivo, labels, labeling, Labels, and, Stains, 6182, Tocris Bioscience

篇 Pimonidazole 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Pimonidazole 的引用文献。 您是否知道使用了 Tocris Pimonidazole 的优秀论文？ 请告知我们.

Pimonidazole 的评论

平均评分: 5 (Based on 1 Review.)

5 星
100%
4 星
0%
3 星
0%
2 星
0%
1 星
0%

Have you used Pimonidazole?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


PIMO detects the levels of hypoxia in Glioblastoma 3D spheres.
By sara Azeem on 01/08/2020
分析类型： In Vitro
种属： Human
细胞系/组织： E2

Glioblstoma patient derived cell line E2 was cultured in a 3D model for 21 days and the level of hypoxia in the spheres were measured following treatment with Pimonidazole.

review image

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals