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Submit Reviewpp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.
分子量 | 1543.5 |
公式 | C62H95N16O28P |
序列 |
TSTEPQYQPGENL (Modifications: Tyr-7 = pTyr) |
储存 | Store at -20°C |
CAS Number | 149299-77-4 |
PubChem ID | 16137939 |
InChI Key | QTTDEIYNMOIHBO-VVTMTNTLSA-N |
Smiles | [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Harder et al (1994) Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 298 395 PMID: 8135747
Roussel et al (1991) Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60c-src. Proc.Natl.Acad.Sci.U.S.A. 88 10696 PMID: 1720546
关键词: pp60 c-src (521-533) (phosphorylated), pp60 c-src (521-533) (phosphorylated) supplier, inhibitors, inhibits, tyrosine, kinase, activity, pp60c-src, pp60v-src, Src, Kinases, 1923, Tocris Bioscience
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