pp60 c-src (521-533) (phosphorylated)

Discontinued Product

1923 has been discontinued.

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说明: Inhibits tyrosine kinase activity of pp60c-src and pp60v-src
说明书
引用文献
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生物活性 for pp60 c-src (521-533) (phosphorylated)

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.

技术数据 for pp60 c-src (521-533) (phosphorylated)

分子量 1543.5
公式 C62H95N16O28P
序列 TSTEPQYQPGENL

(Modifications: Tyr-7 = pTyr)

储存 Store at -20°C
CAS Number 149299-77-4
PubChem ID 16137939
InChI Key QTTDEIYNMOIHBO-VVTMTNTLSA-N
Smiles [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for pp60 c-src (521-533) (phosphorylated)

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参考文献 for pp60 c-src (521-533) (phosphorylated)

参考文献是支持产品生物活性的出版物。

Harder et al (1994) Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 298 395 PMID: 8135747

Roussel et al (1991) Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60c-src. Proc.Natl.Acad.Sci.U.S.A. 88 10696 PMID: 1720546

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关键词: pp60 c-src (521-533) (phosphorylated), pp60 c-src (521-533) (phosphorylated) supplier, inhibitors, inhibits, tyrosine, kinase, activity, pp60c-src, pp60v-src, Src, Kinases, 1923, Tocris Bioscience

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