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Se-NADA

Cat. No. 7449 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Orange fluorescent benzoselenadiazole D-amino acid (FDAA) for imaging bacteria; also photosensitizer
化学名： 3-((7-Nitro-2,1,3-benzoselenadiazol-4-yl)amino)-D-alanine hydrochloride
纯度： ≥95% (HPLC)
说明书
引用文献
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生物活性 Scientific Data 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Se-NADA

Se-NADA is an orange fluorescent benzoselenadiazole D-amino acid (FDAA) for imaging bacteria. It is covalently incorporated into peptidoglycans in the cell walls of live bacteria. It also acts as a photosensitizer, bringing about bacterial cell death on exposure to visible light. Se-NADA is effective against both Gram-positive and Gram-negative bacteria. Ex/Em = 470/590 nm.

Scientific Data

Fluorescence Imaging Application of Se-NADA in B subtilis bacteria cells View Larger

Application of Se-NADA in B subtilis bacteria cells. Fluorescence microscopy image of B subtilis bacterial cells treated with SeNADA (250 μM, red) proving incorporation of the D-amino acid into the peptidoglycans of the cell wall. Image kindly provided by Dr Erkin Kuru, Department of Genetics, Harvard Medical School, Boston.

许可信息

Sold under license from the University of Edinburgh

Optical Data for Se-NADA

Se-NADA Dye Spectra
Emission Color Orange
λabs 470 nm
λem 590 nm
Cell Permeable Yes
Application Fluorescence Microscopy

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

技术数据 for Se-NADA

分子量 366.62
公式 C9H9N5O4Se.HCl
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2571574-70-2
InChI Key NGEWTJCJCRCRQS-PGMHMLKASA-N
Smiles N[C@@H](C(O)=O)CNC1=CC=C(N(=O)=O)C2=N[Se]N=C12.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Se-NADA

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 3.67 10

制备储备液 for Se-NADA

以下数据基于产品分子量 366.62。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 27.28 mL 136.38 mL 272.76 mL
0.5 mM 5.46 mL 27.28 mL 54.55 mL
1 mM 2.73 mL 13.64 mL 27.28 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

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参考文献 for Se-NADA

参考文献是支持产品生物活性的出版物。

Benson et al (2021) Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo. Nat Commun 12 2369 PMID: 33888691

If you know of a relevant reference for Se-NADA, please let us know.

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关键词: Se-NADA, Se-NADA supplier, Fluorescence, imaging, Fluorescent, D-amino, acid, FDAA, labeling, labelling, peptidoglycans, bacteria, bacterial, cell, wall, benzoselenadiazole, photosensitizer, Probes, for, Imaging, Bacteria, Antibiotics, 7449, Tocris Bioscience

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该领域的文献

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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