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说明： Reagent for staining and detection of lipofuscin in senescent cells
化学名： (2-Methyl-6-((E)-(4-((E)-phenyldiazenyl)naphthalen-1-yl)diazenyl)-2,3-dihydro-1H-perimidin-2-yl)methyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate
纯度： ≥95% (HPLC)
生物活性 for SenTraGor™
SenTraGor™ is a reagent for detecting lipofuscin in senescent cells. A highly lipophilic and biotinylated analog of Sudan Black B; can be detected using an anti-biotin antibody. Can be used in vivo and in vitro in any biological material including cell cultures, fresh and frozen tissues, and fixed embedded samples. Compatible with immunohistochemistry, flow cytometry and immunofluorescence analysis.
许可信息
Sold under license from University of Manchester Innovation Factory
技术数据 for SenTraGor™
| 分子量 | 698.85 |
| 公式 | C39H38N8O3S |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 2171036-89-6 |
| PubChem ID | 166603878 |
| InChI Key | NCGWNTJOKSLKQK-SPNFGPMXSA-N |
| Smiles | [H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(OCC3(C)NC4=CC=CC5=C4C(N3)=CC=C5/N=N/C6=CC=C(C7=C6C=CC=C7)/N=N/C8=CC=CC=C8)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for SenTraGor™
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| ethanol | 6.99 | 10 温和加热 | |
| DMSO | 13.98 | 20 |
制备储备液 for SenTraGor™
以下数据基于产品分子量 698.85。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 7.15 mL | 35.77 mL | 71.55 mL |
| 1 mM | 1.43 mL | 7.15 mL | 14.31 mL |
| 2 mM | 0.72 mL | 3.58 mL | 7.15 mL |
| 10 mM | 0.14 mL | 0.72 mL | 1.43 mL |
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产品说明书 for SenTraGor™
参考文献 for SenTraGor™
参考文献是支持产品生物活性的出版物。
Evangelou et al (2017) Robust, universal biomarker assay to detect senescent cells in biological specimens Aging Cell 16 192 PMID: 28165661
If you know of a relevant reference for SenTraGor™, please let us know.
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关键词: SenTraGor™, SenTraGor™ supplier, sudan, black, B, lipofuscin, biotin, biotinylated, senescent, senescence, detection, detector, biomarker, GL13, Labels, and, Stains, 7555, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Fluorescent Dyes and Probes Research Product Guide
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals