Y-27632 in solution

Pricing Availability   Qty
说明: Sterile-filtered 10 mM solution of Y-27632 pre-dissolved in water
化学名: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
纯度: ≥97% (HPLC)
说明书
引用文献
评论
文献 (3)

生物活性 for Y-27632 in solution

Y-27632 in solution is a convenient and ready-to-use 10 mM sterile-filtered solution of Y-27632 (Cat. No. 1254), pre-dissolved in water. Increases survival rate of human embryonic stem (hES) cells and iPSC undergoing cryopreservation. Optimizes naive human pluripotent stem cell growth and viability following naive cell derivation from primed ESCs and iPSCs using naive human stem cell medium (NHSM). Used as a component of growth media for urothelial organoids and in a protocol to generate brain organoids from human iPSCs.

Supplied in vials containing a minimum of 1 mL of Y-27632 solution.

技术数据 for Y-27632 in solution

分子量 320.26
公式 C14H21N3O.2HCl
储存 Store at -20°C
纯度 ≥97% (HPLC)
CAS Number 129830-38-2
PubChem ID 9901617
InChI Key IDDDVXIUIXWAGJ-LJDSMOQUSA-N
Smiles N[C@H](C)[C@@]1([H])CC[C@H](C(NC2=CC=NC=C2)=O)CC1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Y-27632 in solution

溶解性 Soluble in water (supplied pre-dissolved at a concentration of 10mM)

产品说明书 for Y-27632 in solution

参考文献 for Y-27632 in solution

参考文献是支持产品生物活性的出版物。

Schafer et al (2023) An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell 186 2111 PMID: 37172564

Wilson et al (2016) Cryopreservation of brain endothelial cells derived from human induced pluripotent stem cells is enhanced by Rho-associated coiled coil-containing kinase inhibition. Tissue.Eng.Part C.Methods 22 1085 PMID: 27846787

Ichikawa et al (2011) Freeze-thawing single human embryonic stem cells induce e-cadherin and actin filament network disruption via g13 signaling. Cryo Letters 32 516 PMID: 22227712


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