Ubiquitin E3 Ligase Other

Cat. No. Product Name / Activity
7857 BDY FL Lenalidomide
Fluorescent cereblon ligand
7633 BDY FL Thalidomide
High affinity fluorescent probe for TR-FRET cereblon binding assay
7483 BDY FL VH032
High-affinity VHL fluorescent probe for TR-FRET and FP assays
7287 FAM-DEALA-Hyp-YIPD
Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity
6782 Indisulam
Molecular glue; pre-mRNA splicing modulator
6305 Lenalidomide
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
6302 Pomalidomide
Cereblon binder; also TNF-α inhibitor and antiangiogenic
7288 Thalidomide-Cyanine 5
High affinity cereblon fluorescent probe