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Submit Review[Ala107]-MBP (104-118)
Description: Protein kinase C inhibitor
Alternative Names: [Ala107]-Myelin Basic Protein (104-118)
Biological Activity for [Ala107]-MBP (104-118)
[Ala107]-MBP (104-118) is a synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).
Technical Data for [Ala107]-MBP (104-118)
| M. Wt | 1493.68 |
| Formula | C67H104N20O19 |
| Sequence | GKGAGLSLSRFSWGA |
| Storage | Desiccate at -20°C |
| CAS Number | 99026-77-4 |
| PubChem ID | 71312080 |
| InChI Key | PKKMMDDHSZRJTF-NBRSAOMZSA-N |
| Smiles | [H]NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for [Ala107]-MBP (104-118)
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References for [Ala107]-MBP (104-118)
References are publications that support the biological activity of the product.
Su et al (1986) Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem.Biophys.Res.Commun. 134 78 PMID: 2418828
Turner et al (1985) Substrate specificity of phospholipid/Ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. J.Biol.Chem. 260 11503 PMID: 2413012
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Keywords: [Ala107]-MBP (104-118), [Ala107]-MBP (104-118) supplier, Protein, kinase, C, inhibitors, inhibits, PKC, Kinases, [Ala107]-MBP104-118, [Ala107]-Myelin, Basic, (104-118), Kinase, 1900, Tocris Bioscience
Citations for [Ala107]-MBP (104-118)
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