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D-erythro-Sphingosine (synthetic)

Cat. No. 0633 Submit a Review Datasheet / COA / SDS

Discontinued Product

0633 has been discontinued.

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Description: Protein kinase C inhibitor
Chemical Name: trans-D-erythro-2-Amino-4-octadecene-1,3-diol
Datasheet
Citations
Reviews
Biological Activity Technical Data Datasheets References

Biological Activity for D-erythro-Sphingosine (synthetic)

D-erythro-Sphingosine (synthetic) is an inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.

Technical Data for D-erythro-Sphingosine (synthetic)

M. Wt 299.5
Formula C18H37NO2
Storage Store at -20°C
CAS Number 123-78-4
PubChem ID 5280335
InChI Key WWUZIQQURGPMPG-KRWOKUGFSA-N
Smiles N[C@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for D-erythro-Sphingosine (synthetic)

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for D-erythro-Sphingosine (synthetic)

References are publications that support the biological activity of the product.

Grossman (1990) Sphingosine inhibition and promotion of histamine release from isolated rat mast cells. Agents Actions 31 171 PMID: 1707581

Merrill et al (1989) Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds. Biochemistry 28 3138 PMID: 2742830

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Keywords: D-erythro-Sphingosine (synthetic), D-erythro-Sphingosine (synthetic) supplier, Protein, kinase, C, inhibitors, inhibits, PKC, Kinases, Kinase, 0633, Tocris Bioscience

Citations for D-erythro-Sphingosine (synthetic)

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Currently there are no citations for D-erythro-Sphingosine (synthetic).

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