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Submit ReviewDLin-KC2-DMA New
Description: Ionizable cationic lipid
Chemical Name: 2-[2,2-Di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Purity: ≥95% (HPLC)
Biological Activity for DLin-KC2-DMA
DLin-KC2-DMA is an ionisable cationic lipid (pKa = 6.7), used in combination with other lipids in the formation of lipid nanoparticles (LNPs) encapsulating siRNA or plasmid DNA for highly effective and non-toxic delivery into cells in vitro and in vivo.
Technical Data for DLin-KC2-DMA
| M. Wt | 642.11 |
| Formula | C43H79NO2 |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 1190197-97-7 |
| PubChem ID | 44464860 |
| InChI Key | LRFJOIPOPUJUMI-KWXKLSQISA-N |
| Smiles | C(CCCCCCC/C=C\C/C=C\CCCCC)C1(CCCCCCCC/C=C\C/C=C\CCCCC)OC(CCN(C)C)CO1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for DLin-KC2-DMA
| Solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 100mg/mL) |
Product Datasheets for DLin-KC2-DMA
References for DLin-KC2-DMA
References are publications that support the biological activity of the product.
Kulkarni et al (2017) Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine 13 1377 PMID: 28038954
If you know of a relevant reference for DLin-KC2-DMA, please let us know.
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Keywords: DLin-KC2-DMA, DLin-KC2-DMA supplier, Dlin, KC2, DMA, LNP, lipid, nanoparticles, in, vivo, mRNA, cDNA, reagent, Biochemicals, and, Molecular, Biology, Lipid, transfection, Nanoparticles, 8895, Tocris Bioscience
Citations for DLin-KC2-DMA
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