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Submit ReviewIRDye® 680RD, Maleimide New
Description: Near-infared dye (reactive group maleimide)
Chemical Name: Sodium (Z)-2-((2Z,4E)-5-(5-Chloro-3,3-dimethyl-7-(3-sulfonatopropyl)-3H-pyrrolo[2,3-b]pyridin-7-ium-2-yl)-3-(3-(3-((2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-3-oxopropyl)phenyl)penta-2,4-dien-1-ylidene)-3,3-dimethyl-1-(3-sulfonatopropyl)indoline-5-sulfonate
Purity: ≥80% (HPLC)
Biological Activity for IRDye® 680RD, Maleimide
Key information: IRDye® 680RD, Maleimide is a near-infrared (NIR) fluorescent dye, supplied with a maleimide reactive group for conjugation (thiol reactivity).
Application: Fluorescence microscopy.
Properties and Photophysical Data: Excitation and emission maxima (λ) are 680 nm and 694 nm, respectively.
Please see the product protocol for further information and a guide to protein/antibody labeling.
It is recommended to dissolve dye in water or DMSO (10 - 20 mg/mL)
Optical Data for IRDye® 680RD, Maleimide
| λabs | 680 nm |
|---|---|
| λem | 694 nm |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
Technical Data for IRDye® 680RD, Maleimide
| M. Wt | 1028.51 |
| Formula | C45H48ClN5Na2O12S3 |
| Storage | Store at -20°C |
| Purity | ≥80% (HPLC) |
| CAS Number | 1373919-90-4 |
| InChI Key | WNABCDILPZNFNW-UHFFFAOYSA-L |
| Smiles | O=S(C1=CC(C/2(C)C)=C(C=C1)N(CCCS(=O)(O[Na])=O)C2=C/C=C(C3=CC(CCC(NCCN4C(C=CC4=O)=O)=O)=CC=C3)/C=C/C5=NC6=[N+](CCCS([O-])(=O)=O)C=C(Cl)C=C6C5(C)C)(O[Na])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for IRDye® 680RD, Maleimide
References for IRDye® 680RD, Maleimide
References are publications that support the biological activity of the product.
Sestito et al (2023) Lymphatic-draining nanoparticles deliver Bay K8644 payload to lymphatic vessels and enhance their pumping function. Sci.Adv. 9 eabq0435 PMID: 36827374
If you know of a relevant reference for IRDye® 680RD, Maleimide, please let us know.
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Keywords: IRDye® 680RD, Maleimide, IRDye® 680RD, Maleimide supplier, NIR, near, infrared, short, wave, SWIR, fluorescent, dyes, fluorescence, imaging, labeling, labelling, Near, Infrared, Fluorescent, (NIR), Dyes, 8877, Tocris Bioscience
Citations for IRDye® 680RD, Maleimide
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Fluorescent Dyes and Probes Research Product Guide
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
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