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Submit ReviewPIM-1 Inhibitor 2
Description: Pim-1 kinase inhibitor
Chemical Name: 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
Purity: ≥98% (HPLC)
Biological Activity for PIM-1 Inhibitor 2
PIM-1 Inhibitor 2 is a potent Pim-1 kinase inhibitor (Ki = 91 nM).
Technical Data for PIM-1 Inhibitor 2
| M. Wt | 322.75 |
| Formula | C17H11ClN4O |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 477845-12-8 |
| PubChem ID | 2765355 |
| InChI Key | AQVFETGXIRKVAQ-UHFFFAOYSA-N |
| Smiles | NC1=NC=CC(C3=CC2=C(C4=CC=C(Cl)C=C4)ON=C2C=C3)=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for PIM-1 Inhibitor 2
References for PIM-1 Inhibitor 2
References are publications that support the biological activity of the product.
Pierce et al (2008) Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase. J.Med.Chem. 51 1972 PMID: 18290603
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Keywords: PIM-1 Inhibitor 2, PIM-1 Inhibitor 2 supplier, Pim-1, kinase, inhibitors, inhibits, kinases, PIM-1, Inhibitor2, Pim, Kinase, 3589, Tocris Bioscience
1 Citation for PIM-1 Inhibitor 2
Citations are publications that use Tocris products. Selected citations for PIM-1 Inhibitor 2 include:
Yin et al (2013) Inhibition of the Pim1 oncogene results in diminished visual function. PLoS One 7 e52177 PMID: 23300608
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