Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Reviewpp60 c-src (521-533) (phosphorylated)
Description: Inhibits tyrosine kinase activity of pp60c-src and pp60v-src
Biological Activity for pp60 c-src (521-533) (phosphorylated)
pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.
Technical Data for pp60 c-src (521-533) (phosphorylated)
| M. Wt | 1543.5 |
| Formula | C62H95N16O28P |
| Sequence |
TSTEPQYQPGENL (Modifications: Tyr-7 = pTyr) |
| Storage | Store at -20°C |
| CAS Number | 149299-77-4 |
| PubChem ID | 16137939 |
| InChI Key | QTTDEIYNMOIHBO-VVTMTNTLSA-N |
| Smiles | [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for pp60 c-src (521-533) (phosphorylated)
References for pp60 c-src (521-533) (phosphorylated)
References are publications that support the biological activity of the product.
Harder et al (1994) Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 298 395 PMID: 8135747
Roussel et al (1991) Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60c-src. Proc.Natl.Acad.Sci.U.S.A. 88 10696 PMID: 1720546
View Related Products by Target
View Related Products by Product Action
Keywords: pp60 c-src (521-533) (phosphorylated), pp60 c-src (521-533) (phosphorylated) supplier, inhibitors, inhibits, tyrosine, kinase, activity, pp60c-src, pp60v-src, Src, Kinases, 1923, Tocris Bioscience
Citations for pp60 c-src (521-533) (phosphorylated)
Citations are publications that use Tocris products.
Currently there are no citations for pp60 c-src (521-533) (phosphorylated).
Reviews for pp60 c-src (521-533) (phosphorylated)
There are currently no reviews for this product. Be the first to review pp60 c-src (521-533) (phosphorylated) and earn rewards!
Have you used pp60 c-src (521-533) (phosphorylated)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image