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2B-(SP)

Cat. No. 1802 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1802 has been discontinued.

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说明： Selective GSK-3 phosphopeptide substrate
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for 2B-(SP)

2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3); derived from the phosphorylation site of the translation factor eIF2B.

技术数据 for 2B-(SP)

分子量 1835.88
公式 C71H123N26O29P
序列 RRAAEELDSRAGSPQL

(Modifications: Ser-13 = pSer)
储存 Desiccate at -20°C
CAS Number 186901-17-7
PubChem ID 90488714
InChI Key LBVCQYQHTKHZRY-APZQELAWSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](COP(O)(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for 2B-(SP)

参考文献是支持产品生物活性的出版物。

Welsh et al (1997) Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Anal.Biochem. 244 16 PMID: 9025901

Williams et al (1999) Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3β and Shaggy. FEBS Lett. 448 86 PMID: 10217415

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关键词: 2B-(SP), 2B-(SP) supplier, Selective, GSK-3, phosphopeptide, Glycogen, Synthase, Kinases, 3, Carbohydrate, Metabolism, Enzyme, Substrates, activators, 2BSP, /, Activators, Kinase, 1802, Tocris Bioscience

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