Click N-Acetylmuramic acid - azide

Cat. No. 7506 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes

化学名： (2R)-2-(((3R,4R,5S,6R)-3-(2-Azidoacetamido)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanoic acid

纯度： ≥95% (HPLC)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Click N-Acetylmuramic acid - azide

Click N-Acetylmuramic acid-azide is a derivative of the N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. Incorporated into bacterial peptidoglycans during biosynthesis. Suitable for fluorescent labeling of peptidoglycans when ''click'-conjugated to a fluorescent dye.

许可信息

Sold under license from the University of Delaware

技术数据 for Click N-Acetylmuramic acid - azide

分子量	334.29
公式	C₁₁H₁₈N₄O₈
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	2245794-64-1
InChI Key	BDRSICZLRYBNHJ-HONWWXKESA-N
Smiles	C[C@H](C(O)=O)O[C@H]1[C@@H]([C@H](OC([C@@H]1NC(CN=[N+]=[N-])=O)O)CO)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Click N-Acetylmuramic acid - azide

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	1.67	5

制备储备液 for Click N-Acetylmuramic acid - azide

以下数据基于产品分子量 334.29。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.05 mM	59.83 mL	299.14 mL	598.28 mL
0.25 mM	11.97 mL	59.83 mL	119.66 mL
0.5 mM	5.98 mL	29.91 mL	59.83 mL
2.5 mM	1.2 mL	5.98 mL	11.97 mL

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产品说明书 for Click N-Acetylmuramic acid - azide

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Click N-Acetylmuramic acid - azide

参考文献是支持产品生物活性的出版物。

Liang et al (2017) Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications. Nat. Commun. 8 15015 PMID: 28425464

DeMeester et al (2018) Synthesis of functionalized N-acetyl muramic acids to probe bacterial cell wall recycling and biosynthesis. J.Am.Chem.Soc. 140 9458 PMID: 29986130

Wodzanowski et al (2020) Tools for probing host-bacteria interactions in the gut microenvironment: from molecular to cellular levels. Bioorg.Med.Chem.Lett. 30 127116 PMID: 32223923

Wodzanowski et al (2022) Multiscale invasion assay for probing macrophage response to gram-negative bacteria. Front.Chem. 10 842602 PMID: 35242744

Taylor et al (2021e) Localizing peptidoglycan synthesis in helicobacter pylori using clickable metabolic probes. Curr.Protoc. 1 e80 PMID: 33844460

If you know of a relevant reference for Click N-Acetylmuramic acid - azide, please let us know.

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