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Cyclapolin 9

Cat. No. 3116 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3116 has been discontinued.

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说明： Selective, ATP-competitive PLK1 inhibitor
化学名： 7-Nitro-5-(trifluoromethyl)-2-benzothiazolecarboxamide-3-oxide
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for Cyclapolin 9

Cyclapolin 9 is a selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC50 = 500 nM).

技术数据 for Cyclapolin 9

分子量 307.21
公式 C9H4F3N3O4S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 40533-25-3
PubChem ID 2779952
InChI Key FHFLXKUKCSDMLD-UHFFFAOYSA-N
Smiles [O-][N+]2=C(C(N)=O)SC1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Cyclapolin 9

参考文献是支持产品生物活性的出版物。

Taylor et al (2008) Ligand discovery and virtual screening using the program LIDAEUS. Br.J.Pharmacol. 153 S55 PMID: 18037921

McInnes et al (2006) Inhibitors of polo-like kinase reveal roles in spindle pole maintenance. Nature Chem.Biol. 2 608

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关键词: Cyclapolin 9, Cyclapolin 9 supplier, Selective, ATP-competitive, PLK1, inhibitors, inhibits, Polo-like, Kinase, Kinases, Cyclapolin9, Mitosis, 3116, Tocris Bioscience

1 篇 Cyclapolin 9 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Cyclapolin 9 的部分引用包括：

Cozzoli et al (2012) Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures. Proc Natl Acad Sci U S A 36 1623 PMID: 22432643

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