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DBHDA

Cat. No. 6175 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Reagent for synthetic biology; converts cysteine to dehydroalanine
化学名： 2,5-Dibromohexanediamide
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for DBHDA

DBHDA is a reagent for synthetic biology; converts cysteine to dehydroalanine (Dha).

技术数据 for DBHDA

分子量 301.96
公式 C6H10Br2N2O2
储存 Store at +4°C
CAS Number 99584-96-0
PubChem ID 277410
InChI Key PLSXNAQEJOGNKQ-UHFFFAOYSA-N
Smiles NC(C(CCC(C(N)=O)Br)Br)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for DBHDA

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 30.2 100

制备储备液 for DBHDA

以下数据基于产品分子量 301.96。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.31 mL 16.56 mL 33.12 mL
5 mM 0.66 mL 3.31 mL 6.62 mL
10 mM 0.33 mL 1.66 mL 3.31 mL
50 mM 0.07 mL 0.33 mL 0.66 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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参考文献 for DBHDA

参考文献是支持产品生物活性的出版物。

Chalker et al (2011) Methods for converting cysteine to dehydroalanine on peptides and proteins. Chem. Sci. 2 1666

Wright et al (2016) Posttranslational mutagenesis: a chemical strategy for exploring protein side-chain diversity. Science 354 1465 PMID: 27708059

Mulder et al (2016) A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol. 12 523 PMID: 27182664

Lercher et al (2015) Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation. Nat.Commun. 25 7978 PMID: 26305776

If you know of a relevant reference for DBHDA, please let us know.

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关键词: DBHDA, DBHDA supplier, diacetamide, reagent, synthetic, biology, converts, cysteine, dehydroalanine, Dha, Biochemicals, and, Molecular, Biology, 6175, Tocris Bioscience

1 篇 DBHDA 的引用文献

引用文献是使用了 Tocris 产品的出版物。 DBHDA 的部分引用包括：

Andrew J et al (2023) Posttranslational, site-directed photochemical fluorine editing of protein sidechains to probe residue oxidation state via 19F-nuclear magnetic resonance. Nat Protoc 18 1543-1562 PMID: 36806799

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