Deferoxamine mesylate

Cat. No. 5764 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Iron chelator; also hypoxia mimetic and neuroprotectant

化学名： N⁴-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-N¹-(5-aminopentyl)-N¹-hydroxybutanediamide methanesulfonate

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Deferoxamine mesylate

Deferoxamine mesylate is an iron chelator. Also hypoxia mimetic and inhibitor of ferroptosis. Has neuroprotective effects in animal models of stroke, traumatic brain injury and neurodegenerative diseases.

技术数据 for Deferoxamine mesylate

分子量	656.79
公式	C₂₅H₄₈N₆O₈.CH₄O₃S
储存	Store at -20°C
CAS Number	138-14-7
PubChem ID	62881
InChI Key	IDDIJAWJANBQLJ-UHFFFAOYSA-N
Smiles	ON(C(CCC(NCCCCCN(C(CCC(NCCCCCN(O)C(C)=O)=O)=O)O)=O)=O)CCCCCN.CS(=O)(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Deferoxamine mesylate

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	65.68	100

制备储备液 for Deferoxamine mesylate

以下数据基于产品分子量 656.79。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	1.52 mL	7.61 mL	15.23 mL
5 mM	0.3 mL	1.52 mL	3.05 mL
10 mM	0.15 mL	0.76 mL	1.52 mL
50 mM	0.03 mL	0.15 mL	0.3 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for Deferoxamine mesylate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Deferoxamine mesylate

参考文献是支持产品生物活性的出版物。

Chau et al (2005) Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors. Cancer Res. 65 4918 PMID: 15930314

Kosyakovsky et al (2019) Quantifying intranasally administered deferoxamine in rat brain tissue with mass spectrometry. ACS Chem.Neurosci. 10 4571 PMID: 31573798

If you know of a relevant reference for Deferoxamine mesylate, please let us know.

按标靶查看相关产品

关键词: Deferoxamine mesylate, Deferoxamine mesylate supplier, iron, metal, chelator, hypoxia, ferroptosis, inhibitors, inhibits, Biochemicals, and, Molecular, Biology, Hypoxia, Inducible, Factors, 5764, Tocris Bioscience

篇 Deferoxamine mesylate 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Deferoxamine mesylate 的引用文献。您是否知道使用了 Tocris Deferoxamine mesylate 的优秀论文？请告知我们.