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Submit ReviewDL-Dithiothreitol is a reagent for maintaining SH groups in the reduced state.
分子量 | 154.25 |
公式 | C4H10O2S2 |
储存 | Store at +4°C |
纯度 | ≥98% |
CAS Number | 3483-12-3 |
PubChem ID | 51341375 |
InChI Key | DCRJBUYBNCQKEE-CKQOXSRLSA-N |
Smiles | SC[C@H](O)[C@@H](O)CS.SC[C@@H](O)[C@H](O)CS |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 15.42 | 100 |
以下数据基于产品分子量 154.25。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 6.48 mL | 32.41 mL | 64.83 mL |
5 mM | 1.3 mL | 6.48 mL | 12.97 mL |
10 mM | 0.65 mL | 3.24 mL | 6.48 mL |
50 mM | 0.13 mL | 0.65 mL | 1.3 mL |
参考文献是支持产品生物活性的出版物。
Rüegg and Rudinger (1977) Reductive cleavage of cystine disulfides with tributylphosphine. Methods Enzymol. 47 111 PMID: 927167
Sears et al (1977) Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry 16 2031 PMID: 403938
Jabusch et al (1978) The effect of thiodiglycol and dithiothreitol on the alkaline hydrolysis products of certain amino acid phenylthiohydantoins. Anal.Biochem. 91 532 PMID: 9762140
Cleland (1964) Dithiothreitol, a new protective group for SH groups. Biochemistry 3 480 PMID: 14192894
If you know of a relevant reference for DL-Dithiothreitol, please let us know.
关键词: DL-Dithiothreitol, DL-Dithiothreitol supplier, Maintains, SH, groups, reduced, state, Reagents, Clelands, reagent, DTT, Cleland's, Sputolysin, Biochemicals, and, Molecular, Biology, 3154, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 DL-Dithiothreitol 的部分引用包括:
Baca et al (2013) Gene-environment interactions affect long-term depression (LTD) through changes in DA receptor affinity in Snap25 deficient mice. Brain Res 1532 85 PMID: 23939223
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