EGTA

Cat. No. 2807 6 篇引用文献 2 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Calcium chelating agent

化学名： Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid

说明书

引用文献 (6)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for EGTA

EGTA is a calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.

技术数据 for EGTA

分子量	380.35
公式	C₁₄H₂₄N₂O₁₀
储存	Store at RT
CAS Number	67-42-5
PubChem ID	6207
InChI Key	DEFVIWRASFVYLL-UHFFFAOYSA-N
Smiles	O=C(CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for EGTA

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	1M NaOH	38.03	100

制备储备液 for EGTA

以下数据基于产品分子量 380.35。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.63 mL	13.15 mL	26.29 mL
5 mM	0.53 mL	2.63 mL	5.26 mL
10 mM	0.26 mL	1.31 mL	2.63 mL
50 mM	0.05 mL	0.26 mL	0.53 mL

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产品说明书 for EGTA

分析证书/产品说明书

化学品安全技术说明书

参考文献 for EGTA

参考文献是支持产品生物活性的出版物。

Boullerne et al (2001) Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. J.Neurosci.Res. 63 124 PMID: 11169622

Fisher et al (2004) Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochem.Biophy.Res.Comms. 323 163

If you know of a relevant reference for EGTA, please let us know.

按标靶查看相关产品

关键词: EGTA, EGTA supplier, Calcium, chelating, agent, Reagents, Signaling, Signalling, Agents, General, Ca2+, Biochemicals, and, Molecular, Biology, 2807, Tocris Bioscience

6 篇 EGTA 的引用文献

引用文献是使用了 Tocris 产品的出版物。 EGTA 的部分引用包括：

Lerner et al (2010) Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30 2160 PMID: 20147543

Shambharkar et al (2015) TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. BMC Complement Altern Med 10 e0127480 PMID: 25996873

Ahn et al (2015) Neuroprotection and spatial memory enhancement of four herbal mixture extract in HT22 hippocampal cells and a mouse model of focal cerebral ischemia. Carcinogenesis 15 202 PMID: 26122524

Chang et al (2013) Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition. PLoS One 34 1096 PMID: 23349021

Zhang et al (2011) Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition. Biochim Biophys Acta 1808 1993 PMID: 21570948

Gouet et al (2012) On the mechanism of synaptic depression induced by CaMKIIN, an endogenous inhibitor of CaMKII. PLoS One 7 e49293 PMID: 23145145

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EGTA 的评论

平均评分: 4.5 (基于 2 条评论。)

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EGTA activates CRAC current via passive ER Ca2+ depletion in HEK293 cells co-expressing YFP-STIM1 and Orai1-CFP..

By Anonymous on 12/16/2018

分析类型： In Vitro

种属： Human

细胞系/组织： HEK293

ER Ca2+ in HEK293 cells co-expressing YFP-STIM1 and Orai1-CFP was passively depleted with pipette solution, containing (in mM): 20 EGTA, 145 Cs-methanesulfonate, 8 NaCl, 5 MgCl2 and 10 HEPES, pH 7.2 with KOH.

EGTA inhibits 15d-PGJ2 induced TNFa production by cardiomyocytes.

By Anonymous on 12/10/2018