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说明： Selective inhibitor of CK2. Also inhibits glutathione S-transferase
化学名： 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
纯度： ≥99% (HPLC)
生物活性 for Ellagic acid
Ellagic acid is a selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase.
技术数据 for Ellagic acid
| 分子量 | 302.19 |
| 公式 | C14H6O8 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 476-66-4 |
| PubChem ID | 5281855 |
| InChI Key | AFSDNFLWKVMVRB-UHFFFAOYSA-N |
| Smiles | OC1=C(O)C=C(C(C3=C2C=C(O)C(O)=C3O4)=C1OC2=O)C4=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Ellagic acid
参考文献 for Ellagic acid
参考文献是支持产品生物活性的出版物。
Cozza et al (2006) Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J.Med.Chem. 49 2363 PMID: 16610779
Han et al (2006) Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res. 26 3601 PMID: 17094489
Hayeshi et al (2007) The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem.Toxicol. 45 286 PMID: 17046132
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关键词: Ellagic acid, Ellagic acid supplier, Selective, CK2, inhibits, inhibitors, glutathione, S-transferase, Casein, Kinase, 2, Transferases, Other, 3058, Tocris Bioscience
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