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HaXS8

Cat. No. 4991 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Chemical dimerizer
化学名： N-[[4-[[(2-Amino-9-H-purin-6-yl)oxy]methyl]phenyl]methyl]-2-[4-[(18-chloro-3,6,9,12-tetraoxaoctadec-1yl)oxy]-2,3,5,6-tetrafluorophenoxy]acetamide
纯度： ≥90% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for HaXS8

HaXS8 is a chemical dimerizer that promotes covalent and irreversible HaloTag® and SNAP-tag® substrate dimerization. Cell permeable.

HaloTag is a trademark of Promega Corporation, and SNAP-tag is a trademark of New England BioLabs, Inc.

技术数据 for HaXS8

分子量 787.2
公式 C35H43ClF4N6O8
储存 Store at -20°C
纯度 ≥90% (HPLC)
CAS Number 2080306-25-6
PubChem ID 124201846
InChI Key OHHUCZCSUXJJFO-UHFFFAOYSA-N
Smiles NC1=NC2=C(N=CN2)C(OCC3=CC=C(CNC(COC4=C(F)C(F)=C(OCCOCCOCCOCCOCCCCCCCl)C(F)=C4F)=O)C=C3)=N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for HaXS8

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 78.72 100

制备储备液 for HaXS8

以下数据基于产品分子量 787.2。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.27 mL 6.35 mL 12.7 mL
5 mM 0.25 mL 1.27 mL 2.54 mL
10 mM 0.13 mL 0.64 mL 1.27 mL
50 mM 0.03 mL 0.13 mL 0.25 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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产品说明书 for HaXS8

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for HaXS8

参考文献是支持产品生物活性的出版物。

Erhart et al (2013) Chemical development of intracellular protein heterodimerizers. Chem.Biol. 20 549 PMID: 23601644

Zimmermann et al (2014) Cell-permeant and photocleavable chemical inducer of dimerization. Angew Chem.Int.Ed.Engl. 53 4717 PMID: 24677313

If you know of a relevant reference for HaXS8, please let us know.

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关键词: HaXS8, HaXS8 supplier, promotes, covalent, irreversible, HaloTag, SNAP-tag, dimerization, dimerizer, cell, permeable, Biochemicals, and, Molecular, Biology, Protein, Dimerizers, 4991, Tocris Bioscience

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