2-Hydroxypropyl-β-cyclodextrin

Pricing Availability   Qty
说明: Solubilization agent
别名: HBC,Hydroxypropyl-β-cyclodextrin
说明书
引用文献 (2)
评论

生物活性 for 2-Hydroxypropyl-β-cyclodextrin

The most widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with HBC.

技术数据 for 2-Hydroxypropyl-β-cyclodextrin

分子量 1400
公式 (C6H9O5)7(C3H7O)n
储存 Store at RT
CAS Number 128446-35-5
PubChem ID 44134771
InChI Key BZRWCHBEBFPRGF-UHFFFAOYSA-N
Smiles O[C@@H]1[C@H]8C(COCC(C)O)O[C@H](O[C@H](C(COCC(C)O)O[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O[C@H](C(COCC(C)O)O[C@H](O[C@@H]5C(O)C(O)[C@H](O[C@@H]6C(O)C(O)[C@H](O[C@H](C(COCC(C)O)O[C@H](O8)[C@H]7O)[C@H]7O)O[C@@H]6COCC(C)O)O[C@@H]5COCC(C)O)[C@H]4O)[C@@H]4O)OC3COCC(C)O)[C@H]2O)[C@H]2O)[C@H]1O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 2-Hydroxypropyl-β-cyclodextrin

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 140 100

制备储备液 for 2-Hydroxypropyl-β-cyclodextrin

以下数据基于产品分子量 1400。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 0.71 mL 3.57 mL 7.14 mL
5 mM 0.14 mL 0.71 mL 1.43 mL
10 mM 0.07 mL 0.36 mL 0.71 mL
50 mM 0.01 mL 0.07 mL 0.14 mL

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产品说明书 for 2-Hydroxypropyl-β-cyclodextrin

分析证书/产品说明书
选择另一批次:

参考文献 for 2-Hydroxypropyl-β-cyclodextrin

参考文献是支持产品生物活性的出版物。

Frijlink (1991) The effects of cyclodextrins on the disposition of intravenously injected drugs in the rat. Pharm.Res. 8 380 PMID: 2052529

Pitha et al (1986) Hydroxypropyl-β-cyclodextrin: preparation and characterisation; effects on solubility of drugs. Int.J.Pharmacol. 29 73


If you know of a relevant reference for 2-Hydroxypropyl-β-cyclodextrin, please let us know.

按标靶查看相关产品

关键词: Hydroxypropyl-b-cyclodextrin, Hydroxypropyl-b-cyclodextrin supplier, Solubilization, agent, Reagents, cyclodextrin, Hydroxypropyl-beta-cyclodextrin, Hydroxypropyl-β-cyclodextrin, HBC, Hydroxypropyl-b-cyclodextrin, Biochemicals, and, Molecular, Biology, 0708, Tocris Bioscience

2 篇 2-Hydroxypropyl-β-cyclodextrin 的引用文献

引用文献是使用了 Tocris 产品的出版物。 2-Hydroxypropyl-β-cyclodextrin 的部分引用包括:

Marco et al (2016) Optogenetically enhanced pituitary corticotroph cell activity post-stress onset causes rapid organizing effects on behaviour. Nat Commun 7 12620 PMID: 27646867

Johnson et al (2012) Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network. Proc Natl Acad Sci U S A 107 733 PMID: 22554617


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