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说明： Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging.
化学名： Sodium 4-(2-((1E,3E,5E,7Z)-7-(1,1-Dimethyl-3-(4-sulfonatobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl-1,2,3,4,5,6,7-d7)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate
纯度： ≥95% (HPLC)
生物活性 for ICG-d7
Key information: ICG-d7 is a partially deuterated form of near-infrared fluorescent dye Indocyanine Green (ICG; Cat. No. 7510).
Application: Fluorescence microscopy, in vivo imaging.
Properties and Photophysical Data: ICG-d7 operates in the 700 - 900 nm wavelength range; also exhibits fluorescence emission in the shortwave infrared window (SWIR; 1,000 - 2,000 nm) which enables in vivo imaging. ICG-d7 shows improved stability in aqueous solutions over ICG with the same fluorescence brightness, and similar absorption and emission maxima in both DMSO and FBS. Excitation and emission maxima (λ) are 794 nm and 818 nm, respectively; quantum yield = 0.21; extinction coefficient = 228,000 M-1cm-1.
许可信息
Sold under license from the University of Notre Dame
Optical Data for ICG-d7
| Emission Color | Near-IR |
|---|---|
| λabs | 794 nm |
| λem | 818 nm |
| Extinction Coefficient (ε) | 228000 M-1cm-1 |
| Quantum Yield (φ) | 0.21 |
| Application | Fluorescence Microscopy, In Vivo Imaging |
| Alternative For | Indocyanine green |
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技术数据 for ICG-d7
| 分子量 | 782.01 |
| 公式 | C43H40D7N2O6S2Na |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 2861905-57-7 |
| InChI Key | MOFVSTNWEDAEEK-ZMRQXZMGSA-M |
| Smiles | CC1(C)/C(N(CCCCS(=O)(O[Na])=O)C2=C1C3=CC=CC=C3C=C2)=C(/C([2H])=C(/C([2H])=C(/C([2H])=C(C4=[N+](CCCCS([O-])(=O)=O)C5=C(C6=CC=CC=C6C=C5)C4(C)C)\[2H])[2H])[2H])[2H] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for ICG-d7
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 7.82 | 10 | |
| DMSO | 7.82 | 10 |
制备储备液 for ICG-d7
以下数据基于产品分子量 782.01。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.79 mL | 63.94 mL | 127.88 mL |
| 0.5 mM | 2.56 mL | 12.79 mL | 25.58 mL |
| 1 mM | 1.28 mL | 6.39 mL | 12.79 mL |
| 5 mM | 0.26 mL | 1.28 mL | 2.56 mL |
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产品说明书 for ICG-d7
参考文献 for ICG-d7
参考文献是支持产品生物活性的出版物。
Li and Smith (2021) Deuterated indocyanine green (ICG) with extended aqueous storage shelf-life: chemical and clinical implications. Chemistry 27 14535 PMID: 34403531
If you know of a relevant reference for ICG-d7, please let us know.
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关键词: ICG-d7, ICG-d7 supplier, ICGd7, indocyanine, cyanine, green, deuterated, deuterium, NIR, near, infrared, fluorescent, fluorescence, stable, stability, short, wave, infra, red, labeling, Near, Infrared, (NIR), Fluorescent, Dyes, Cyanine, (Cy, Dyes), Stable, Isotopically, Labeled, Compounds, 7749, Tocris Bioscience
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Fluorescent Dyes and Probes Research Product Guide
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