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Submit ReviewLithium carbonate
说明： Mood stabilizer; inhibits GSK-3 in vivo
化学名： Carbonic acid dilithium salt
生物活性 for Lithium carbonate
Lithium carbonate is a mood stabilizer; thought to act by reducing catecholamine neurotransmitter concentration, through an effect on the Na+/K+ ATPase pump. Effective in the treatment of bipolar disorder. Inhibits GSK-3 in vivo.
技术数据 for Lithium carbonate
| 分子量 | 73.89 |
| 公式 | Li2CO3 |
| 储存 | Store at RT |
| CAS Number | 554-13-2 |
| PubChem ID | 11125 |
| InChI Key | XGZVUEUWXADBQD-UHFFFAOYSA-L |
| Smiles | [Li+].[Li+].[O-]C([O-])=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Lithium carbonate
参考文献 for Lithium carbonate
参考文献是支持产品生物活性的出版物。
Lenox and Hahn (2000) Overview of the mechanism of action of Li in the brain: fifty-year update. J.Clin.Psychiatry 61 5 PMID: 10826655
Gould et al (2004) In vivo evidence in the brain for Li inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29 32 PMID: 12942141
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关键词: Lithium carbonate, Lithium carbonate supplier, Mood, stabilizers, sodium, potassium, Na+/K+, ATPase, pumps, bipolar, Glycogen, Synthase, Kinase, 3, 4740, Tocris Bioscience
⚠ WARNING: This product can expose you to chemicals including Lithium carbonate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov
1 篇 Lithium carbonate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Lithium carbonate 的部分引用包括：
Irene et al (2018) Automatic quantification of juvenile zebrafish aggression. J Neurosci Methods 296 23-31 PMID: 29274793
Lithium carbonate 的评论
平均评分: 5 (Based on 1 Review.)
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Li2CO3 prolongs cardiac action potential duration.
By
Chintan Koyani on 10/23/2018
分析类型： In Vitro
种属： Other
细胞系/组织： Ventricular cardiomyocytes
Guinea pig ventricular cardiomyocytes were patched and stimulated at a 1 Hz frequency to record action potentials before and after Li2CO3 (10 and 30 µM). Li2CO3 significantly prolonged action potential duration at 20% and 90% repolarization levels.
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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Pathways for Lithium carbonate
