PP 3

Cat. No. 2794 7 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Negative control for PP 2 (Cat. No. 1407)

化学名： 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

纯度： ≥98% (HPLC)

说明书

引用文献 (7)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for PP 3

PP 3 is a negative control for the Src kinase inhibitor, PP 2. Inhibits EGFR kinase (IC₅₀ = 2.7 μM).

Active Analog also available.

化合物库 for PP 3

PP 3 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Antiviral Library. 了解 Tocris 化合物库的更多信息。

技术数据 for PP 3

分子量	211.22
公式	C₁₁H₉N₅
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	5334-30-5
PubChem ID	4879
InChI Key	KKDPIZPUTYIBFX-UHFFFAOYSA-N
Smiles	NC1=NC=NC2=C1C=NN2C3=CC=CC=C3

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for PP 3

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	21.12	100
	ethanol	5.28	25

制备储备液 for PP 3

以下数据基于产品分子量 211.22。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	4.73 mL	23.67 mL	47.34 mL
5 mM	0.95 mL	4.73 mL	9.47 mL
10 mM	0.47 mL	2.37 mL	4.73 mL
50 mM	0.09 mL	0.47 mL	0.95 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for PP 3

分析证书/产品说明书

化学品安全技术说明书

参考文献 for PP 3

参考文献是支持产品生物活性的出版物。

Traxler et al (1997) Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines. J.Med.Chem. 40 3601 PMID: 9357527

Hou et al (2007) PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia. Neurosci.Letts. 420 235 PMID: 17556100

If you know of a relevant reference for PP 3, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Src Kinase Inhibitors

关键词: PP 3, PP 3 supplier, Negative, control, PP, 2, EGFR-kinases, inhibitors, inhibits, Src, negative, Epidermal, Growth, Factors, Receptors, ErbB, Her, EGFR, Receptor, Tyrosine, RTKs, PP3, Kinases, 2794, Tocris Bioscience