ProK

Cat. No. 7361 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Unnatural amino acid, propargyl lysine derivative

化学名： N⁶-[(2-Propyn-1-yloxy)carbonyl]-L-lysine hydrochloride

纯度： ≥95%

说明书

引用文献

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for ProK

ProK is a lysine-based unnatural amino acid (UAA) used for genetic code expansion. It enables bioconjugation of fluorescent probes in E. coli or multicellular organisms.

技术数据 for ProK

分子量	264.71
公式	C₁₀H₁₆N₂O₄.HCl
储存	Store at -20°C
纯度	≥95%
CAS Number	1428330-91-9
PubChem ID	118898827
InChI Key	ZYUXGVUWYHHZTD-QRPNPIFTSA-N
Smiles	C(NCCCC[C@@H](C(O)=O)N)(OCC#C)=O.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for ProK

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	26.47	100
	water	26.47	100

制备储备液 for ProK

以下数据基于产品分子量 264.71。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.78 mL	18.89 mL	37.78 mL
5 mM	0.76 mL	3.78 mL	7.56 mL
10 mM	0.38 mL	1.89 mL	3.78 mL
50 mM	0.08 mL	0.38 mL	0.76 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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产品说明书 for ProK

分析证书/产品说明书

化学品安全技术说明书

参考文献 for ProK

参考文献是支持产品生物活性的出版物。

Nguyen et al (2009) Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry. J.Am.Chem.Soc. 131 8720 PMID: 19514718

Neumann et al (2010) Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. Nature 464 441 PMID: 20154731

Li et al (2014) Palladium-triggered deprotection chemistry for protein activation in living cells. Nat. Chem. 6 352 PMID: 24651204

Greiss et al (2011) Expanding the genetic code of an animal. J.Am.Chem.Soc. 133 14196 PMID: 21819153

Meineke et al (2020) Site-specific incorporation of two ncAAs for two-color bioorthogonal labeling and crosslinking of proteins on live mammalian cells. Cell Rep. 31 107811 PMID: 32579937

If you know of a relevant reference for ProK, please let us know.

按标靶查看相关产品

Unnatural Amino Acids / Non Canonical Amino Acids

关键词: ProK, ProK supplier, unnatural, amino, acid, protein, non-canonical, tagging, labeling, labelling, UAA, Amino, Acids, Unnatural, 7361, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

Fluorescent Dyes, including dyes for flow cytometry
Fluorescent Probes and Stains, including our new MitoBrilliant^TM mitochondria stains
Tissue Clearing Kits and Reagents
Aptamer-based RNA Imaging Reagents
Fluorescent Probes for Imaging Bacteria
TSA Vivid^TM Fluorophore Kits
TSA Reagents for Enhancing IHC, ICC & FISH Signals